Christina Applegate is an American actress and producer, born on November 25, 1971, in Hollywood, Los Angeles, California. She is best known for her roles in television series such as “Married… with Children,” where she portrayed Kelly Bundy, and “Dead to Me,” for which she received critical acclaim and multiple award nominations.
In 2021, Applegate was diagnosed with multiple sclerosis (MS), a chronic illness affecting the central nervous system. She has since been open about her health challenges, including frequent hospitalizations due to severe gastrointestinal symptoms.
In March 2025, she revealed that she had been hospitalized “upwards of 30 times” over the past three years for issues such as vomiting, diarrhea, and pain, which she believes are related to MS.
Despite these health struggles, Applegate continues to engage in creative projects. She co-hosts the podcast “MeSsy” with fellow actress Jamie-Lynn Sigler, where they discuss their experiences living with MS. The podcast offers a candid look into their lives, providing support and fostering a sense of community among listeners facing similar challenges.
In November 2022, Applegate received a star on the Hollywood Walk of Fame, with her “Married… with Children” co-stars Katey Sagal and David Faustino present at the ceremony. Reflecting on her career, she expressed gratitude for the opportunities she has had and the support from fans and colleagues.
Applegate’s openness about her health journey and her continued dedication to her craft have garnered admiration from fans and peers alike, highlighting her resilience and commitment to raising awareness about MS.