In their 2025 season opener on March 27, the Baltimore Orioles defeated the Toronto Blue Jays 12-2 at Rogers Centre in Toronto.
The Orioles set a franchise record by hitting six home runs in the game. Cedric Mullins and Adley Rutschman each hit two home runs, while Tyler O’Neill added a three-run homer, extending his record to six consecutive Opening Day home runs.
Starting pitcher Zach Eflin earned the win, allowing two runs on four hits over six innings. José Berríos took the loss for Toronto, giving up six runs on nine hits in five innings.